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» Geometry of gene expression dynamics
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BIOCOMP
2008
13 years 9 months ago
Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2005
178views more  BMCBI 2005»
13 years 7 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
BMCBI
2011
13 years 2 months ago
A Platform for Processing Expression of Short Time Series (PESTS)
Background: Time course microarray profiles examine the expression of genes over a time domain. They are necessary in order to determine the complete set of genes that are dynamic...
Anshu Sinha, Marianthi Markatou
BMCBI
2006
88views more  BMCBI 2006»
13 years 7 months ago
Effect of various normalization methods on Applied Biosystems expression array system data
Background: DNA microarray technology provides a powerful tool for characterizing gene expression on a genome scale. While the technology has been widely used in discovery-based m...
Catalin C. Barbacioru, Yulei Wang, Roger D. Canale...
BMCBI
2007
155views more  BMCBI 2007»
13 years 7 months ago
Current approaches to gene regulatory network modelling
Many different approaches have been developed to model and simulate gene regulatory networks. We proposed the following categories for gene regulatory network models: network part...
Thomas Schlitt, Alvis Brazma