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» Goal-oriented Analysis of Regulations
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124
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WSC
1997
15 years 5 months ago
On the Efficiency of the Splitting and Roulette Approach for Sensitivity Analysis
The paper is devoted to a brief review of a mathematical theory for the branching variance-reduction technique. The branching technique is an extension of von Neumann’s splittin...
Viatcheslav B. Melas
99
Voted
BMCBI
2008
114views more  BMCBI 2008»
15 years 3 months ago
The pairwise disconnectivity index as a new metric for the topological analysis of regulatory networks
Background: Currently, there is a gap between purely theoretical studies of the topology of large bioregulatory networks and the practical traditions and interests of experimental...
Anatolij Potapov, Björn Goemann, Edgar Wingen...
146
Voted
BMCBI
2005
102views more  BMCBI 2005»
15 years 3 months ago
Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...
141
Voted
BIOCOMP
2007
15 years 5 months ago
Stability Analysis of Genetic Regulatory Network with Additive Noises
Background: Genetic regulatory networks (GRN) can be described by differential equations with SUM logic which has been found in many natural systems. Identification of the network...
Yufang Jin
115
Voted
BMCBI
2005
89views more  BMCBI 2005»
15 years 3 months ago
Comparative analysis of chromatin landscape in regulatory regions of human housekeeping and tissue specific genes
Background: Global regulatory mechanisms involving chromatin assembly and remodelling in the promoter regions of genes is implicated in eukaryotic transcription control especially...
Mythily Ganapathi, Pragya Srivastava, Sushanta Kum...