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BMCBI
2007
99views more  BMCBI 2007»
13 years 9 months ago
The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data
Background: The combination of mass spectrometry and solution phase amide hydrogen/deuterium exchange (H/D exchange) experiments is an effective method for characterizing protein ...
B. D. Pascal, M. J. Chalmers, S. A. Busby, C. C. M...
BMCBI
2007
133views more  BMCBI 2007»
13 years 8 months ago
Semi-supervised learning for the identification of syn-expressed genes from fused microarray and in situ image data
Background: Gene expression measurements during the development of the fly Drosophila melanogaster are routinely used to find functional modules of temporally co-expressed genes. ...
Ivan G. Costa, Roland Krause, Lennart Opitz, Alexa...
BMCBI
2010
115views more  BMCBI 2010»
13 years 9 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
SIGMOD
2006
ACM
116views Database» more  SIGMOD 2006»
14 years 9 months ago
Provenance management in curated databases
Curated databases in bioinformatics and other disciplines are the result of a great deal of manual annotation, correction and transfer of data from other sources. Provenance infor...
Peter Buneman, Adriane Chapman, James Cheney
BMCBI
2007
105views more  BMCBI 2007»
13 years 9 months ago
Generating confidence intervals on biological networks
Background: In the analysis of networks we frequently require the statistical significance of some network statistic, such as measures of similarity for the properties of interact...
Thomas Thorne, Michael P. H. Stumpf