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BMCBI
2010
120views more  BMCBI 2010»
13 years 7 months ago
Examination of the relationship between essential genes in PPI network and hub proteins in reverse nearest neighbor topology
Background: In many protein-protein interaction (PPI) networks, densely connected hub proteins are more likely to be essential proteins. This is referred to as the "centralit...
Kang Ning, Hoong Kee Ng, Sriganesh Srihari, Hon Wa...
BMCBI
2006
146views more  BMCBI 2006»
13 years 7 months ago
GeneTools - application for functional annotation and statistical hypothesis testing
Background: Modern biology has shifted from "one gene" approaches to methods for genomic-scale analysis like microarray technology, which allow simultaneous measurement ...
Vidar Beisvag, Frode K. R. Jünge, Hallgeir Be...
BMCBI
2010
138views more  BMCBI 2010»
13 years 7 months ago
UFFizi: a generic platform for ranking informative features
Background: Feature selection is an important pre-processing task in the analysis of complex data. Selecting an appropriate subset of features can improve classification or cluste...
Assaf Gottlieb, Roy Varshavsky, Michal Linial, Dav...
BMCBI
2007
207views more  BMCBI 2007»
13 years 7 months ago
Discovering biomarkers from gene expression data for predicting cancer subgroups using neural networks and relational fuzzy clus
Background: The four heterogeneous childhood cancers, neuroblastoma, non-Hodgkin lymphoma, rhabdomyosarcoma, and Ewing sarcoma present a similar histology of small round blue cell...
Nikhil R. Pal, Kripamoy Aguan, Animesh Sharma, Shu...
BMCBI
2010
92views more  BMCBI 2010»
13 years 7 months ago
Integrating gene expression and GO classification for PCA by preclustering
Background: Gene expression data can be analyzed by summarizing groups of individual gene expression profiles based on GO annotation information. The mean expression profile per g...
Jorn R. de Haan, Ester Piek, René C. van Sc...