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NAR
2011
12 years 11 months ago
2011
Allostery is the most direct, rapid and efficient way of regulating protein function, ranging from the control of metabolic mechanisms to signaltransduction pathways. However, an ...
NAR
2011
2011
FragmentStore - a comprehensive database of fragments linking metabolites, toxic molecules and drugs
12 years 11 months ago
Consideration of biomolecules in terms of their molecular building blocks provides valuable new information regarding their synthesis, degradation and similarity. Here, we present...
NAR
2011
2011
NGSmethDB: a database for next-generation sequencing single-cytosine-resolution DNA methylation data
12 years 11 months ago
Next-generation sequencing (NGS) together with bisulphite conversion allows the generation of whole genome methylation maps at single-cytosine resolution. This allows studying the...
NAR
2011
12 years 11 months ago
2011
The initiation and regulation of transcription in eukaryotes is complex and involves a large number of transcription factors (TFs), which are known to bind to the regulatory regio...
NAR
2011
12 years 11 months ago
2011
High-throughput genomic technologies have been used to explore personal human genomes for the past few years. Although the integration of technologies is important for high-accura...