Allostery is the most direct, rapid and efficient way of regulating protein function, ranging from the control of metabolic mechanisms to signaltransduction pathways. However, an ...
Zhimin Huang, Liang Zhu, Yan Cao, Geng Wu, Xinyi L...
Consideration of biomolecules in terms of their molecular building blocks provides valuable new information regarding their synthesis, degradation and similarity. Here, we present...
Jessica Ahmed, Catherine L. Worth, Paul Florian Th...
Next-generation sequencing (NGS) together with bisulphite conversion allows the generation of whole genome methylation maps at single-cytosine resolution. This allows studying the...
Michael Hackenberg, Guillermo Barturen, José...
The initiation and regulation of transcription in eukaryotes is complex and involves a large number of transcription factors (TFs), which are known to bind to the regulatory regio...
Ulf Schaefer, Sebastian Schmeier, Vladimir B. Baji...
High-throughput genomic technologies have been used to explore personal human genomes for the past few years. Although the integration of technologies is important for high-accura...
Dongwan Hong, Sung-Soo Park, Young Seok Ju, Sheehy...