Optimizations aimed at reducing the impact of memory operations on execution speed have long concentrated on improving cache performance. These efforts achieve a reasonable level...
To cope with the increasing difference between processor and main memory speeds, modern computer systems use deep memory hierarchies. In the presence of such hierarchies, the perf...
Margaret Martonosi, Anoop Gupta, Thomas E. Anderso...
In this paper we describe a new technique, called pipeline spectroscopy, and use it to measure the cost of each cache miss. The cost of a miss is displayed (graphed) as a histogra...
Thomas R. Puzak, Allan Hartstein, Philip G. Emma, ...
Background: In structural genomics, an important goal is the detection and classification of protein–protein interactions, given the structures of the interacting partners. We h...
Guillaume Launay, Raul Mendez, Shoshana J. Wodak, ...
Resolving the general organizational principles that govern the interactions during transcriptional gene regulation has great relevance for understanding disease progression, biof...