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ASPLOS
1998
ACM
14 years 1 months ago
Compiler-Controlled Memory
Optimizations aimed at reducing the impact of memory operations on execution speed have long concentrated on improving cache performance. These efforts achieve a reasonable level...
Keith D. Cooper, Timothy J. Harvey
SIGMETRICS
1992
ACM
128views Hardware» more  SIGMETRICS 1992»
14 years 27 days ago
MemSpy: Analyzing Memory System Bottlenecks in Programs
To cope with the increasing difference between processor and main memory speeds, modern computer systems use deep memory hierarchies. In the presence of such hierarchies, the perf...
Margaret Martonosi, Anoop Gupta, Thomas E. Anderso...
CF
2007
ACM
14 years 25 days ago
An analysis of the effects of miss clustering on the cost of a cache miss
In this paper we describe a new technique, called pipeline spectroscopy, and use it to measure the cost of each cache miss. The cost of a miss is displayed (graphed) as a histogra...
Thomas R. Puzak, Allan Hartstein, Philip G. Emma, ...
BMCBI
2007
115views more  BMCBI 2007»
13 years 8 months ago
Recognizing protein-protein interfaces with empirical potentials and reduced amino acid alphabets
Background: In structural genomics, an important goal is the detection and classification of protein–protein interactions, given the structures of the interacting partners. We h...
Guillaume Launay, Raul Mendez, Shoshana J. Wodak, ...
JCB
2008
90views more  JCB 2008»
13 years 8 months ago
A Simple Model of the Modular Structure of Transcriptional Regulation in Yeast
Resolving the general organizational principles that govern the interactions during transcriptional gene regulation has great relevance for understanding disease progression, biof...
Vladimir Filkov, Nameeta Shah