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BMCBI
2008
195views more  BMCBI 2008»
13 years 8 months ago
Goldsurfer2 (Gs2): A comprehensive tool for the analysis and visualization of genome wide association studies
Background: Genome wide association (GWA) studies are now being widely undertaken aiming to find the link between genetic variations and common diseases. Ideally, a well-powered G...
Fredrik Pettersson, Andrew P. Morris, Michael R. B...
BMCBI
2010
243views more  BMCBI 2010»
13 years 8 months ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...
BMCBI
2007
122views more  BMCBI 2007»
13 years 8 months ago
TAP score: torsion angle propensity normalization applied to local protein structure evaluation
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
Silvio C. E. Tosatto, Roberto Battistutta
AAI
2006
106views more  AAI 2006»
13 years 8 months ago
Metaheuristics for Handling Time Interval Coverage Constraints in Nurse Scheduling
The problem of finding a high quality timetable for personnel in a hospital ward has been addressed by many researchers, personnel managers and schedulers over a number of years. ...
Edmund K. Burke, Patrick De Causmaecker, Sanja Pet...
BMCBI
2007
135views more  BMCBI 2007»
13 years 8 months ago
Automatic extraction of reliable regions from multiple sequence alignments
Background: High quality multiple alignments are crucial in the transfer of annotation from one genome to another. Multiple alignment methods strive to achieve ever increasing lev...
Timo Lassmann, Erik L. L. Sonnhammer