392 search results - page 10 / 79 » High-Precision Function Prediction using Conserved Interacti... |
BMCBI
2008
13 years 8 months ago
2008
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
RECOMB
2007
Springer
14 years 9 months ago
2007
Springer
We describe an algorithm, IsoRank, for global alignment of two protein-protein interaction (PPI) networks. IsoRank aims to maximize the overall match between the two networks; in c...
ICDM
2006
IEEE
14 years 2 months ago
2006
IEEE
There is a need to develop methods to automatically incorporate prior knowledge to support the prediction and validation of novel functional associations. One such important sourc...
BMCBI
2008
13 years 8 months ago
2008
Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
RECOMB
2003
Springer
14 years 9 months ago
2003
Springer
Background: Transcriptional regulation in eukaryotes often involves multiple transcription factors binding to the same transcription control region, and to understand the regulato...