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BIBE
2007
IEEE
129views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
Statistial Analysis of nucleosome occupancy and histone modification data
Abstract-- In eukaryotic cells, genomic DNAs wrap around beadlike molecules, called nucleosomes, so as to pack more compactly in the nucleus of the cell. The nucleosome is made up ...
Guo-Cheng Yuan, Jun S. Liu
ESANN
2004
13 years 10 months ago
Sparse LS-SVMs using additive regularization with a penalized validation criterion
This paper is based on a new way for determining the regularization trade-off in least squares support vector machines (LS-SVMs) via a mechanism of additive regularization which ha...
Kristiaan Pelckmans, Johan A. K. Suykens, Bart De ...
BIB
2007
59views more  BIB 2007»
13 years 9 months ago
Statistically designing microarrays and microarray experiments to enhance sensitivity and specificity
Gene expression signatures from microarray experiments promise to provide important prognostic tools for predicting disease outcome or response to treatment. A number of microarra...
Jason C. Hsu, Jane Chang, Tao Wang, Eiríkur...
BMCBI
2010
97views more  BMCBI 2010»
13 years 9 months ago
Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach
Background: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on es...
Dirk Repsilber, Sabine Kern, Anna Telaar, Gerhard ...
BMCBI
2007
172views more  BMCBI 2007»
13 years 9 months ago
msBayes: Pipeline for testing comparative phylogeographic histories using hierarchical approximate Bayesian computation
Background: Although testing for simultaneous divergence (vicariance) across different population-pairs that span the same barrier to gene flow is of central importance to evoluti...
Michael J. Hickerson, Eli Stahl, Naoki Takebayashi