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BMCBI
2004
177views more  BMCBI 2004»
13 years 7 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
SCFBM
2008
92views more  SCFBM 2008»
13 years 7 months ago
CRANKITE: A fast polypeptide backbone conformation sampler
Background: CRANKITE is a suite of programs for simulating backbone conformations of polypeptides and proteins. The core of the suite is an efficient Metropolis Monte Carlo sample...
Alexei A. Podtelezhnikov, David L. Wild
BMCBI
2007
181views more  BMCBI 2007»
13 years 8 months ago
Versatile annotation and publication quality visualization of protein complexes using POLYVIEW-3D
Background: Macromolecular visualization as well as automated structural and functional annotation tools play an increasingly important role in the post-genomic era, contributing ...
Aleksey A. Porollo, Jaroslaw Meller
ICCS
2005
Springer
14 years 1 months ago
Modelling Dynamics of Genetic Networks as a Multiscale Process
A key phenomenon in the dynamics of genetic networks is the cell cycle. In the study of this phenomenon, an important task is to understand how many processes, acting on different...
Xilin Wei, Roderick V. N. Melnik, Gabriel Moreno-H...
BIOSYSTEMS
2008
83views more  BIOSYSTEMS 2008»
13 years 8 months ago
Hydrophobic condensation and modular assembly model of protein folding
Despite several decades of intense study, protein folding problem remains elusive. In this paper, we review current knowledge and the prevailing thinking in the field, and summari...
Tian-Yow Tsong, Chin-Kun Hu, Ming-Chya Wu