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ISMB
1994
13 years 9 months ago
GeneQuiz: A Workbench for Sequence Analysis
Wepresent the prototype of a software system, cMledGeneQuiz,for large-scale biological sequence analysis. The system was designed to meet the needs that arise in computational seq...
Michael Scharf, Reinhard Schneider, Georg Casari, ...
BMCBI
2007
105views more  BMCBI 2007»
13 years 7 months ago
HoxPred: automated classification of Hox proteins using combinations of generalised profiles
Background: Correct identification of individual Hox proteins is an essential basis for their study in diverse research fields. Common methods to classify Hox proteins focus on th...
Morgane Thomas-Chollier, Luc Leyns, Valérie...
BMCBI
2008
189views more  BMCBI 2008»
13 years 7 months ago
AnEnPi: identification and annotation of analogous enzymes
Background: Enzymes are responsible for the catalysis of the biochemical reactions in metabolic pathways. Analogous enzymes are able to catalyze the same reactions, but they prese...
Thomas D. Otto, Ana Carolina R. Guimarães, ...
BMCBI
2006
115views more  BMCBI 2006»
13 years 7 months ago
Detecting recombination in evolving nucleotide sequences
Background: Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. These recombination events can be obscured by subsequent resid...
Cheong Xin Chan, Robert G. Beiko, Mark A. Ragan
BIBE
2008
IEEE
142views Bioinformatics» more  BIBE 2008»
14 years 2 months ago
Optimizing performance, cost, and sensitivity in pairwise sequence search on a cluster of PlayStations
— The Smith-Waterman algorithm is a dynamic programming method for determining optimal local alignments between nucleotide or protein sequences. However, it suffers from quadrati...
Ashwin M. Aji, Wu-chun Feng