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BMCBI
2008
13 years 10 months ago
2008
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
BMCBI
2008
13 years 10 months ago
2008
Background: Many proposed statistical measures can efficiently compare protein sequence to further infer protein structure, function and evolutionary information. They share the s...
BMCBI
2007
13 years 10 months ago
2007
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
BMCBI
2007
13 years 10 months ago
2007
Background: Some distance methods are among the most commonly used methods for reconstructing phylogenetic trees from sequence data. The input to a distance method is a distance m...
BMCBI
2008
13 years 10 months ago
2008
Background: The Golden Spike data set has been used to validate a number of methods for summarizing Affymetrix data sets, sometimes with seemingly contradictory results. Much less...