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BMCBI
2010
2010
An intuitionistic approach to scoring DNA sequences against transcription factor binding site motifs
13 years 9 months ago
Background: Transcription factors (TFs) control transcription by binding to specific regions of DNA called transcription factor binding sites (TFBSs). The identification of TFBSs ...
BMCBI
2008
13 years 9 months ago
2008
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
BMCBI
2008
13 years 9 months ago
2008
Background: Many proposed statistical measures can efficiently compare protein sequence to further infer protein structure, function and evolutionary information. They share the s...
BMCBI
2007
13 years 9 months ago
2007
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
BMCBI
2008
13 years 9 months ago
2008
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...