The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving various...
Zheng Fu, Xin Chen, Vladimir Vacic, Peng Nan, Yang...
Background: A key challenge in systems biology is the reconstruction of an organism's metabolic network from its genome sequence. One strategy for addressing this problem is ...
Background: Alternative splicing (AS) is now considered as a major actor in transcriptome/ proteome diversity and it cannot be neglected in the annotation process of a new genome....
Abstract: The search for local RNA secondary structures and the annotation of unusually stable folding regions in genomic sequences are two well motivated bioinformatic problems. I...
Andreas R. Gruber, Stephan H. F. Bernhart, You Zho...
The molecular diversity of viruses complicates the interpretation of viral genomic and proteomic data. To make sense of viral gene functions, investigators must be familiar with t...
Chantal Hulo, Edouard De Castro, Patrick Masson, L...