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    BMCBI
    2006
    108views more  BMCBI 2006»
    Gene function classification using Bayesian models with hierarchy-based priors
    13 years 10 months ago
    Gene function classification using Bayesian models with hierarchy-based priors
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    We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
    Babak Shahbaba, Radford M. Neal
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    BMCBI
    2006
    141views more  BMCBI 2006»
    The use of concept maps during knowledge elicitation in ontology development processes - the nutrigenomics use case
    13 years 10 months ago
    The use of concept maps during knowledge elicitation in ontology development processes - the nutrigenomics use case
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    Background: Incorporation of ontologies into annotations has enabled 'semantic integration' of complex data, making explicit the knowledge within a certain field. One of...
    Alexander García Castro, Philippe Rocca-Ser...
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    BMCBI
    2007
    145views more  BMCBI 2007»
    Improved benchmarks for computational motif discovery
    13 years 10 months ago
    Improved benchmarks for computational motif discovery
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    Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
    Geir Kjetil Sandve, Osman Abul, Vegard Walseng, Fi...
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    BMCBI
    2007
    182views more  BMCBI 2007»
    Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
    13 years 10 months ago
    Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
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    Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
    Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
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    BMCBI
    2007
    116views more  BMCBI 2007»
    Clustering protein environments for function prediction: finding PROSITE motifs in 3D
    13 years 10 months ago
    Clustering protein environments for function prediction: finding PROSITE motifs in 3D
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    Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
    Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...
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