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» Hybrid Genetic Algorithm for DNA Sequencing with Errors
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BMCBI
2008
108views more  BMCBI 2008»
13 years 7 months ago
Supervised Lowess normalization of comparative genome hybridization data - application to lactococcal strain comparisons
Background: Array-based comparative genome hybridization (aCGH) is commonly used to determine the genomic content of bacterial strains. Since prokaryotes in general have less cons...
Sacha A. F. T. van Hijum, Richard J. S. Baerends, ...
BMCBI
2006
99views more  BMCBI 2006»
13 years 7 months ago
MAGIC-SPP: a database-driven DNA sequence processing package with associated management tools
Background: Processing raw DNA sequence data is an especially challenging task for relatively small laboratories and core facilities that produce as many as 5000 or more DNA seque...
Chun Liang, Feng Sun, Haiming Wang, Junfeng Qu, Ro...
CPM
1999
Springer
99views Combinatorics» more  CPM 1999»
13 years 11 months ago
On the Complexity of Positional Sequencing by Hybridization
In sequencing by hybridization (SBH), one has to reconstruct a sequence from its l-long substrings. SBH was proposed as an alternative to gel-based DNA sequencing approaches, but ...
Amir Ben-Dor, Itsik Pe'er, Ron Shamir, Roded Shara...
RECOMB
2003
Springer
14 years 7 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
GECCO
2004
Springer
137views Optimization» more  GECCO 2004»
14 years 26 days ago
Evolving Better Multiple Sequence Alignments
Aligning multiple DNA or protein sequences is a fundamental step in the analyses of phylogeny, homology and molecular structure. Heuristic algorithms are applied because optimal mu...
Luke Sheneman, James A. Foster