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BMCBI
2010
86views more  BMCBI 2010»
13 years 7 months ago
ICC-CLASS: isotopically-coded cleavable crosslinking analysis software suite
Background: Successful application of crosslinking combined with mass spectrometry for studying proteins and protein complexes requires specifically-designed crosslinking reagents...
Evgeniy V. Petrotchenko, Christoph H. Borchers
BMCBI
2007
166views more  BMCBI 2007»
13 years 7 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
JCB
2008
91views more  JCB 2008»
13 years 7 months ago
Computational Quantification of Peptides from LC-MS Data
Liquid chromatography coupled to mass spectrometry (LC-MS) has become a major tool for the study of biological processes. High-throughput LC-MS experiments are frequently conducte...
Ole Schulz-Trieglaff, Rene Hussong, Clemens Gr&oum...
PAKDD
2004
ACM
131views Data Mining» more  PAKDD 2004»
14 years 1 months ago
A Tree-Based Approach to the Discovery of Diagnostic Biomarkers for Ovarian Cancer
Computational diagnosis of cancer is a classification problem, and it has two special requirements on a learning algorithm: perfect accuracy and small number of features used in t...
Jinyan Li, Kotagiri Ramamohanarao
IJAR
2008
93views more  IJAR 2008»
13 years 7 months ago
Prototype based fuzzy classification in clinical proteomics
Proteomic profiling based on mass spectrometry is an important tool for studies at the protein and peptide level in medicine and health care. Thereby, the identification of releva...
Frank-Michael Schleif, Thomas Villmann, Barbara Ha...