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» Identifying Projected Clusters from Gene Expression Profiles
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BMCBI
2010
214views more  BMCBI 2010»
13 years 7 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
ICDE
2006
IEEE
167views Database» more  ICDE 2006»
14 years 9 months ago
Mining Shifting-and-Scaling Co-Regulation Patterns on Gene Expression Profiles
In this paper, we propose a new model for coherent clustering of gene expression data called reg-cluster. The proposed model allows (1) the expression profiles of genes in a clust...
Xin Xu, Ying Lu, Anthony K. H. Tung, Wei Wang 0010
RECOMB
2007
Springer
14 years 7 months ago
Comparative Analysis of Spatial Patterns of Gene Expression in Drosophila melanogaster Imaginal Discs
Determining the precise spatial extent of expression of genes across different tissues, along with knowledge of the biochemical function of the genes is critical for understanding ...
Cyrus L. Harmon, Parvez Ahammad, Ann Hammonds, Ric...
BMCBI
2008
167views more  BMCBI 2008»
13 years 7 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
BMCBI
2007
207views more  BMCBI 2007»
13 years 7 months ago
Analyzing in situ gene expression in the mouse brain with image registration, feature extraction and block clustering
Background: Many important high throughput projects use in situ hybridization and may require the analysis of images of spatial cross sections of organisms taken with cellular lev...
Manjunatha Jagalur, Chris Pal, Erik G. Learned-Mil...