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» Identifying Structural Motifs in Proteins
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APBC
2004
166views Bioinformatics» more  APBC 2004»
13 years 11 months ago
THEMATICS is Effective for Active Site Prediction in Comparative Model Structures
THEMATICS (Theoretical Microscopic Titration Curves) is a simple, reliable computational predictor of the active sites of enzymes from structure. Our method, based on well-establi...
Ihsan A. Shehadi, Alper Uzun, Leonel F. Murga, Val...
ISMB
1998
13 years 11 months ago
Phylogenetic Inference in Protein Superfamilies: Analysis of SH2 Domains
This workfocuses on the inference of evolutionary relationships in protein superfamilies, and the uses of these relationships to identify keypositions in the structure, to infer a...
Kimmen Sjölander
BMCBI
2006
103views more  BMCBI 2006»
13 years 10 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
NAR
2006
71views more  NAR 2006»
13 years 9 months ago
sgTarget: a target selection resource for structural genomics
sgTarget (http://www.ysbl.york.ac.uk/sgTarget) is a web-based resource to aid the selection and prioritization of candidate proteins for structure determination. The system annota...
Ana P. C. Rodrigues, Barry J. Grant, Roderick E. H...
BMCBI
2007
126views more  BMCBI 2007»
13 years 10 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne