1531 search results - page 185 / 307 » Identifying Topics by Position |
BMCBI
2010
13 years 8 months ago
2010
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
BMCBI
2008
13 years 8 months ago
2008
Background: At intermediate stages of genome assembly projects, when a number of contigs have been generated and their validity needs to be verified, it is desirable to align thes...
BMCBI
2006
13 years 8 months ago
2006
Background: Regulatory modules are segments of the DNA that control particular aspects of gene expression. Their identification is therefore of great importance to the field of mo...
BMCBI
2005
13 years 8 months ago
2005
Background: Regions of interest identified through genetic linkage studies regularly exceed 30 centimorgans in size and can contain hundreds of genes. Traditionally this number is...
BMCBI
2005
13 years 8 months ago
2005
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...