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BMCBI
2007
166views more  BMCBI 2007»
13 years 10 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
INFORMATICALT
2010
142views more  INFORMATICALT 2010»
13 years 8 months ago
Complexity Estimation of Genetic Sequences Using Information-Theoretic and Frequency Analysis Methods
The genetic information in cells is stored in DNA sequences, represented by a string of four letters, each corresponding to a definite type of nucleotides. Genomic DNA sequences a...
Robertas Damasevicius
BMCBI
2005
121views more  BMCBI 2005»
13 years 9 months ago
Automated methods of predicting the function of biological sequences using GO and BLAST
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...
Craig E. Jones, Ute Baumann, Alfred L. Brown
ALIFE
2008
13 years 10 months ago
Hierarchical Self-Organization in the Finitary Process Soup
Current analyses of genomes from numerous species show that the diversity of organism's functional and behavioral characters is not proportional to the number of genes that e...
Olof Görnerup, James P. Crutchfield
IJBRA
2007
89views more  IJBRA 2007»
13 years 9 months ago
Conservative adjustment of permutation p-values when the number of permutations is limited
The permutation procedure is widely used to assess the significance level (p-value) of a test statistic. This approach is asymptotically consistent. In genomics and proteomics st...
Yinglei Lai