DNA microarray experiments generate a substantial amount of information about global gene expression. Gene expression profiles can be represented as points in multi-dimensional sp...
Lu-Yong Wang, Ammaiappan Balasubramanian, Amit Cha...
The validation of clusters discovered in bio-molecular data is a central issue in bioinformatics. Recently, stability-based methods have been successfully applied to the analysis o...
Background: Due to the complex and distributed nature of biological research, our current biological knowledge is spread over many redundant annotation databases maintained by man...
Brad T. Sherman, Da Wei Huang, Qina Tan, Yongjian ...
—A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective d...
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...