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» Improved Phylogenetic Motif Detection Using Parsimony
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BMCBI
2006
202views more  BMCBI 2006»
13 years 7 months ago
Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks
Background: The learning of global genetic regulatory networks from expression data is a severely under-constrained problem that is aided by reducing the dimensionality of the sea...
David J. Reiss, Nitin S. Baliga, Richard Bonneau
BIBM
2008
IEEE
113views Bioinformatics» more  BIBM 2008»
14 years 1 months ago
Towards Site-Based Protein Functional Annotations
Abstract—The exact relationship between protein active centers and protein functions is unclear even after decades of intensive study. To improve the functional prediction abilit...
Seak Fei Lei, Jun Huan
RECOMB
2008
Springer
14 years 7 months ago
A Fast, Alignment-Free, Conservation-Based Method for Transcription Factor Binding Site Discovery
As an increasing number of eukaryotic genomes are being sequenced, comparative studies aimed at detecting regulatory elements in intergenic sequences are becoming more prevalent. M...
Raluca Gordân, Leelavati Narlikar, Alexander...
BMCBI
2007
147views more  BMCBI 2007»
13 years 7 months ago
MaxAlign: maximizing usable data in an alignment
Background: The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for ...
Rodrigo Gouveia-Oliveira, Peter Wad Sackett, Ander...
IV
2005
IEEE
68views Visualization» more  IV 2005»
14 years 1 months ago
Visualisation and Analysis of Network Motifs
Many of the complex networks that occur both in nature and in technology are built up from frequently recurring patterns of basic structural elements. These structural patterns kn...
Weidong Huang, Colin Murray, Xiaobin Shen, Le Song...