11321 search results - page 2212 / 2265 » Improvements to Turing's method |
174
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BMCBI
2010
15 years 6 months ago
2010
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
155
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BMCBI
2010
15 years 6 months ago
2010
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
168
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BMCBI
2008
15 years 6 months ago
2008
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
155
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BMCBI
2007
15 years 6 months ago
2007
Background: Due to the complex and distributed nature of biological research, our current biological knowledge is spread over many redundant annotation databases maintained by man...
168
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BMCBI
2007
15 years 6 months ago
2007
Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...