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BMCBI
2007
15 years 4 months ago
2007
Background: Array comparative genome hybridization (aCGH) provides information about genomic aberrations. Alterations in the DNA copy number may cause the cell to malfunction, lea...
142
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BMCBI
2008
15 years 4 months ago
2008
Background: Large biological data sets, such as expression profiles, benefit from reduction of random noise. Principal component (PC) analysis has been used for this purpose, but ...
126
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BMCBI
2008
15 years 4 months ago
2008
Background: Innumerable biological investigations require comparing collections of molecules, cells or organisms to one another with respect to one or more of their properties. Al...
159
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BMCBI
2007
15 years 4 months ago
2007
Background: With DNA microarray data, selecting a compact subset of discriminative genes from thousands of genes is a critical step for accurate classification of phenotypes for, ...
138
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BMCBI
2008
15 years 4 months ago
2008
Background: We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. The method, named Predikin, identifies key conser...