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BMCBI
2010
100views more  BMCBI 2010»
13 years 10 months ago
A robust method for estimating gene expression states using Affymetrix microarray probe level data
Background: Microarray technology is a high-throughput method for measuring the expression levels of thousand of genes simultaneously. The observed intensities combine a non-speci...
Megu Ohtaki, Keiko Otani, Keiko Hiyama, Naomi Kame...
BMCBI
2010
89views more  BMCBI 2010»
13 years 10 months ago
Enhancing metabolomic data analysis with Progressive Consensus Alignment of NMR Spectra (PCANS)
Background: Nuclear magnetic resonance spectroscopy is one of the primary tools in metabolomics analyses, where it is used to track and quantify changes in metabolite concentratio...
Jennifer M. Staab, Thomas M. O'Connell, Shawn M. G...
BMCBI
2010
81views more  BMCBI 2010»
13 years 10 months ago
Discrete wavelet transform de-noising in eukaryotic gene splicing
Background: This paper compares the most common digital signal processing methods of exon prediction in eukaryotes, and also proposes a technique for noise suppression in exon pre...
Tina P. George, Tessamma Thomas
BMCBI
2008
109views more  BMCBI 2008»
13 years 10 months ago
MetaFIND: A feature analysis tool for metabolomics data
Background: Metabolomics, or metabonomics, refers to the quantitative analysis of all metabolites present within a biological sample and is generally carried out using NMR spectro...
Kenneth Bryan, Lorraine Brennan, Padraig Cunningha...
BMCBI
2007
166views more  BMCBI 2007»
13 years 10 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang