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BIOINFORMATICS
2010
170views more  BIOINFORMATICS 2010»
13 years 9 months ago
Joint estimation of DNA copy number from multiple platforms
DNA copy number variants (CNV) are gains and losses of segments of chromosomes, and comprise an important class of genetic variation. Recently, various microarray hybridization ba...
Nancy R. Zhang, Yasin Senbabaoglu, Jun Z. Li
AUTOMATICA
2007
103views more  AUTOMATICA 2007»
13 years 9 months ago
Lexicographic perturbation for multiparametric linear programming with applications to control
Optimal control problems for constrained linear systems with a linear cost can be posed as multiparametric linear programs with a parameter in the cost, or equivalently the right-...
Colin Neil Jones, Eric C. Kerrigan, Jan M. Maciejo...
BMCBI
2010
86views more  BMCBI 2010»
13 years 9 months ago
A novel approach to simulate gene-environment interactions in complex diseases
Background: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with lar...
Roberto Amato, Michele Pinelli, Daniel D'Andrea, G...
BMCBI
2008
84views more  BMCBI 2008»
13 years 9 months ago
poolHiTS: A Shifted Transversal Design based pooling strategy for high-throughput drug screening
Background: A key goal of drug discovery is to increase the throughput of small molecule screens without sacrificing screening accuracy. High-throughput screening (HTS) in drug di...
Raghunandan M. Kainkaryam, Peter J. Woolf
BMCBI
2007
113views more  BMCBI 2007»
13 years 9 months ago
CoryneRegNet 4.0 - A reference database for corynebacterial gene regulatory networks
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...
Jan Baumbach