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BMCBI
2008
127views more  BMCBI 2008»
13 years 7 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
BMCBI
2008
113views more  BMCBI 2008»
13 years 7 months ago
A novel application of quantile regression for identification of biomarkers exemplified by equine cartilage microarray data
Background: Identification of biomarkers among thousands of genes arrayed for disease classification has been the subject of considerable research in recent years. These studies h...
Liping Huang, Wenying Zhu, Christopher P. Saunders...
BMCBI
2007
123views more  BMCBI 2007»
13 years 7 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
SDM
2008
SIAM
157views Data Mining» more  SDM 2008»
13 years 9 months ago
ROC-tree: A Novel Decision Tree Induction Algorithm Based on Receiver Operating Characteristics to Classify Gene Expression Data
Gene expression information from microarray experiments is a primary form of data for biological analysis and can offer insights into disease processes and cellular behaviour. Suc...
M. Maruf Hossain, Md. Rafiul Hassan, James Bailey
BMCBI
2006
86views more  BMCBI 2006»
13 years 7 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao