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NAR
2010
123views more  NAR 2010»
13 years 2 months ago
Discovering causal signaling pathways through gene-expression patterns
High-throughput gene-expression studies result in lists of differentially expressed genes. Most current meta-analyses of these gene lists include searching for significant members...
Jignesh R. Parikh, Bertram Klinger, Yu Xia, Jarrod...
BMCBI
2007
110views more  BMCBI 2007»
13 years 7 months ago
Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy
Background: The design of long oligonucleotides for spotted DNA microarrays requires detailed attention to ensure their optimal performance in the hybridization process. The main ...
Guangan Hu, Manuel Llinás, Jingguang Li, Pe...
BMCBI
2010
115views more  BMCBI 2010»
13 years 7 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
NN
2007
Springer
267views Neural Networks» more  NN 2007»
13 years 7 months ago
Modeling of gene regulatory networks with hybrid differential evolution and particle swarm optimization
In the last decade, recurrent neural networks (RNNs) have attracted more efforts in inferring genetic regulatory networks (GRNs), using time series gene expression data from micro...
Rui Xu, Ganesh K. Venayagamoorthy, Donald C. Wunsc...
PRIB
2009
Springer
147views Bioinformatics» more  PRIB 2009»
14 years 2 months ago
Cross-Platform Analysis with Binarized Gene Expression Data
Abstract. With widespread use of microarray technology as a potential diagnostics tool, the comparison of results obtained from the use of different platforms is of interest. When...
Salih Tuna, Mahesan Niranjan