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BMCBI
2007
174views more  BMCBI 2007»
13 years 7 months ago
Inferring activity changes of transcription factors by binding association with sorted expression profiles
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
Chao Cheng, Xiting Yan, Fengzhu Sun, Lei M. Li
RECOMB
2005
Springer
14 years 7 months ago
Causal Inference of Regulator-Target Pairs by Gene Mapping of Expression Phenotypes
Background: Correlations between polymorphic markers and observed phenotypes provide the basis for mapping traits in quantitative genetics. When the phenotype is gene expression, ...
David Kulp, Manjunatha Jagalur
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
14 years 20 days ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
AIME
2005
Springer
13 years 9 months ago
An Algorithm to Learn Causal Relations Between Genes from Steady State Data: Simulation and Its Application to Melanoma Dataset
In recent years, a few researchers have challenged past dogma and suggested methods (such as the IC algorithm) for inferring causal relationship among variables using steady state ...
Xin Zhang, Chitta Baral, Seungchan Kim
SAC
2004
ACM
14 years 24 days ago
Time-frequency feature detection for time-course microarray data
Gene clustering based on microarray data provides useful functional information to the working biologists. Many current gene-clustering algorithms rely on Euclidean-based distance...
Jiawu Feng, Paolo Emilio Barbano, Bud Mishra