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» Inference of Reference Immutability
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BMCBI
2008
109views more  BMCBI 2008»
13 years 7 months ago
MetaFIND: A feature analysis tool for metabolomics data
Background: Metabolomics, or metabonomics, refers to the quantitative analysis of all metabolites present within a biological sample and is generally carried out using NMR spectro...
Kenneth Bryan, Lorraine Brennan, Padraig Cunningha...
BMCBI
2007
121views more  BMCBI 2007»
13 years 7 months ago
A constrained polynomial regression procedure for estimating the local False Discovery Rate
Background: In the context of genomic association studies, for which a large number of statistical tests are performed simultaneously, the local False Discovery Rate (lFDR), which...
Cyril Dalmasso, Avner Bar-Hen, Philippe Broët
CORR
2008
Springer
93views Education» more  CORR 2008»
13 years 7 months ago
The end of Sleeping Beauty's nightmare
The way a rational agent changes her belief in certain proposition/hypotheses in the light of new evidence lies in the heart of Bayesian inference. The basic natural assumption, a...
Berry Groisman
BMCBI
2006
87views more  BMCBI 2006»
13 years 7 months ago
Computational expression deconvolution in a complex mammalian organ
Background: Microarray expression profiling has been widely used to identify differentially expressed genes in complex cellular systems. However, while such methods can be used to...
Min Wang, Stephen R. Master, Lewis A. Chodosh
JGS
2006
113views more  JGS 2006»
13 years 7 months ago
Pattern based map comparisons
Map comparison techniques based on a pixel-by-pixel comparison are useful for many purposes, but fail to reveal important aspects of map similarities and differences. In contrast, ...
Roger White