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» Inferring differentiation pathways from gene expression
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BMCBI
2010
97views more  BMCBI 2010»
13 years 8 months ago
Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach
Background: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on es...
Dirk Repsilber, Sabine Kern, Anna Telaar, Gerhard ...
RECOMB
2004
Springer
14 years 9 months ago
Modeling and Analysis of Heterogeneous Regulation in Biological Networks
Abstract. In this study we propose a novel model for the representation of biological networks and provide algorithms for learning model parameters from experimental data. Our appr...
Irit Gat-Viks, Amos Tanay, Ron Shamir
NIPS
2008
13 years 10 months ago
Efficient Sampling for Gaussian Process Inference using Control Variables
Sampling functions in Gaussian process (GP) models is challenging because of the highly correlated posterior distribution. We describe an efficient Markov chain Monte Carlo algori...
Michalis Titsias, Neil D. Lawrence, Magnus Rattray
NAR
2011
191views Computer Vision» more  NAR 2011»
12 years 11 months ago
ConsensusPathDB: toward a more complete picture of cell biology
ConsensusPathDB is a meta-database that integrates different types of functional interactions from heterogeneous interaction data resources. Physical protein interactions, metabol...
Atanas Kamburov, Konstantin Pentchev, Hanna Galick...
BIRD
2008
Springer
141views Bioinformatics» more  BIRD 2008»
13 years 10 months ago
Nested q-Partial Graphs for Genetic Network Inference from "Small n, Large p" Microarray Data
Abstract. Gaussian graphical models are widely used to tackle the important and challenging problem of inferring genetic regulatory networks from expression data. These models have...
Kevin Kontos, Gianluca Bontempi