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» Inferring gene regression networks with model trees
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BMCBI
2006
126views more  BMCBI 2006»
13 years 8 months ago
A joint model of regulatory and metabolic networks
Background: Gene regulation and metabolic reactions are two primary activities of life. Although many works have been dedicated to study each system, the coupling between them is ...
Chen-Hsiang Yeang, Martin Vingron
EVOW
2007
Springer
14 years 2 months ago
Bio-mimetic Evolutionary Reverse Engineering of Genetic Regulatory Networks
The effective reverse engineering of biochemical networks is one of the great challenges of systems biology. The contribution of this paper is two-fold: 1) We introduce a new meth...
Daniel Marbach, Claudio Mattiussi, Dario Floreano
RECOMB
2006
Springer
14 years 9 months ago
Probabilistic Paths for Protein Complex Inference
Understanding how individual proteins are organized into complexes and pathways is a significant current challenge. We introduce new algorithms to infer protein complexes by combin...
Hailiang Huang, Lan V. Zhang, Frederick P. Roth, J...
BMCBI
2010
178views more  BMCBI 2010»
13 years 8 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...

Publication
273views
12 years 6 months ago
 Beyond Graphs: A New Synthesis.
Artificial neural networks, electronic circuits, and gene networks are some examples of systems that can be modeled as networks, that is, as collections of interconnected nodes. I...
Mattiussi, Claudio, Dürr, Peter, Marbach, Daniel ...