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» Inferring subnetworks from perturbed expression profiles
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BMCBI
2006
166views more  BMCBI 2006»
13 years 7 months ago
Extraction of phylogenetic network modules from the metabolic network
Background: In bio-systems, genes, proteins and compounds are related to each other, thus forming complex networks. Although each organism has its individual network, some organis...
Takuji Yamada, Minoru Kanehisa, Susumu Goto
ACSC
2009
IEEE
14 years 2 months ago
Inference of Gene Expression Networks Using Memetic Gene Expression Programming
In this paper we aim to infer a model of genetic networks from time series data of gene expression profiles by using a new gene expression programming algorithm. Gene expression n...
Armita Zarnegar, Peter Vamplew, Andrew Stranieri
JCB
2007
130views more  JCB 2007»
13 years 7 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
BIBE
2006
IEEE
139views Bioinformatics» more  BIBE 2006»
14 years 1 months ago
A Computational Inference Framework for analyzing Gene Regulation Pathway using Microarray Data
Microarray experiments produce gene expression data at such a high speed and volume that it is imperative to use highly specialized computational tools for their analyses. One grou...
Dong-Guk Shin, John Bluis, Yoo Ah Kim, Winfried Kr...
BMCBI
2007
130views more  BMCBI 2007»
13 years 7 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...