Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
The treemap is one of the most popular methods for visualizing hierarchical data. When a treemap contains a large number of items, inspecting or comparing a few selected items in a...
With the exponential growth of complete genome sequences, the analysis of these sequences is becoming a powerful approach to build genome-scale metabolic models. These models can ...
Interactions that determinecellular fate are exceedingly complex, can take place at different levels of gene regulation and involve a large numberof components(such as genes, prot...