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BMCBI
2007
102views more  BMCBI 2007»
13 years 7 months ago
qPIPSA: Relating enzymatic kinetic parameters and interaction fields
Background: The simulation of metabolic networks in quantitative systems biology requires the assignment of enzymatic kinetic parameters. Experimentally determined values are ofte...
Razif R. Gabdoulline, Matthias Stein, Rebecca C. W...
BMCBI
2010
177views more  BMCBI 2010»
13 years 7 months ago
Modular composition predicts kinase/substrate interactions
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
Yichuan Liu, Aydin Tozeren
KDD
2004
ACM
126views Data Mining» more  KDD 2004»
14 years 8 months ago
High-throughput Protein Interactome Data: Minable or Not?
There is an emerging trend in post-genome biology to study the collection of thousands of protein interaction pairs (protein interactome) derived from high-throughput experiments....
Jake Yue Chen, Andrey Y. Sivachenko, Lang Li
COMPLIFE
2005
Springer
14 years 1 months ago
MAPPIS: Multiple 3D Alignment of Protein-Protein Interfaces
A protein-protein interface (PPI) is defined by a pair of regions of two interacting protein molecules that are linked by non-covalent bonds. Recognition of conserved 3D patterns ...
Alexandra Shulman-Peleg, Maxim Shatsky, Ruth Nussi...
BMCBI
2004
120views more  BMCBI 2004»
13 years 7 months ago
An approach to large scale identification of non-obvious structural similarities between proteins
Background: A new sequence independent bioinformatics approach allowing genome-wide search for proteins with similar three dimensional structures has been developed. By utilizing ...
Artem Cherkasov, Steven J. M. Jones