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BMCBI
2010
152views more  BMCBI 2010»
13 years 7 months ago
Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
BMCBI
2010
97views more  BMCBI 2010»
13 years 7 months ago
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
Denis C. Bauer, Fabian A. Buske, Timothy L. Bailey
BMCBI
2007
99views more  BMCBI 2007»
13 years 7 months ago
The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data
Background: The combination of mass spectrometry and solution phase amide hydrogen/deuterium exchange (H/D exchange) experiments is an effective method for characterizing protein ...
B. D. Pascal, M. J. Chalmers, S. A. Busby, C. C. M...
BMCBI
2010
104views more  BMCBI 2010»
13 years 7 months ago
FragViz: visualization of fragmented networks
Background: Researchers in systems biology use network visualization to summarize the results of their analysis. Such networks often include unconnected components, which popular ...
Miha Stajdohar, Minca Mramor, Blaz Zupan, Janez De...
BMCBI
2008
111views more  BMCBI 2008»
13 years 7 months ago
Probabilistic base calling of Solexa sequencing data
Background: Solexa/Illumina short-read ultra-high throughput DNA sequencing technology produces millions of short tags (up to 36 bases) by parallel sequencing-by-synthesis of DNA ...
Jacques Rougemont, Arnaud Amzallag, Christian Isel...