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BMCBI
2010
13 years 10 months ago
2010
Background: Forward-time simulations have unique advantages in power and flexibility for the simulation of genetic samples of complex human diseases because they can closely mimic...
BMCBI
2008
13 years 10 months ago
2008
Background: Multiple sequence alignments are a fundamental tool for the comparative analysis of proteins and nucleic acids. However, large data sets are no longer manageable for v...
BMCBI
2010
13 years 10 months ago
2010
Background: While occurring enzymatically in biological systems, O-linked glycosylation affects protein folding, localization and trafficking, protein solubility, antigenicity, bi...
BMCBI
2008
13 years 10 months ago
2008
Background: Comparative genomics has become a significant research area in recent years, following the availability of a number of sequenced genomes. The comparison of genomes is ...
BMCBI
2007
13 years 10 months ago
2007
Background: Network methods are increasingly used to represent the interactions of genes and/ or proteins. Genes or proteins that are directly linked may have a similar biological...