Background: Knowing which proteins exist in a certain organism or cell type and how these proteins interact with each other are necessary for the understanding of biological proce...
Background: Most proteins function by interacting with other molecules. Their interaction interfaces are highly conserved throughout evolution to avoid undesirable interactions th...
Sungsam Gong, Changbum Park, Hansol Choi, Junsu Ko...
Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Background: Analyzing interaction networks for functional characterization poses significant challenges arising from the noisy, incomplete, and generic nature of both the interact...