116 search results - page 6 / 24 » Invariant features for searching in protein fold databases |
BMCBI
2007
13 years 7 months ago
2007
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
BMCBI
2010
13 years 7 months ago
2010
Background: Protein structure comparison is a fundamental task in structural biology. While the number of known protein structures has grown rapidly over the last decade, searchin...
BMCBI
2010
13 years 7 months ago
2010
Background: Profile hidden Markov models (profile-HMMs) are sensitive tools for remote protein homology detection, but the main scoring algorithms, Viterbi or Forward, require con...
BMCBI
2008
13 years 7 months ago
2008
Background: Subcellular localization information is one of the key features to protein function research. Locating to a specific subcellular compartment is essential for a protein...
BMCBI
2004
13 years 7 months ago
2004
Background: G protein-coupled receptors (GPCRs) transduce signals from extracellular space into the cell, through their interaction with G proteins, which act as switches forming ...