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» Large scale sequencing by hybridization
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BMCBI
2008
117views more  BMCBI 2008»
13 years 7 months ago
CrossHybDetector: detection of cross-hybridization events in DNA microarray experiments
Background: DNA microarrays contain thousands of different probe sequences represented on their surface. These are designed in such a way that potential cross-hybridization reacti...
Paolo Uva, Emanuele de Rinaldis
CSB
2005
IEEE
132views Bioinformatics» more  CSB 2005»
13 years 9 months ago
A Fast Shotgun Assembly Heuristic
Genome sequencing opened a new era in genetics allowing the study of genomes at the nucleotide level. However, the chosen method of sequencing produced large numbers of nucleotide...
Christopher Wilks, Sami Khuri
JCB
2007
130views more  JCB 2007»
13 years 7 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
SC
2000
ACM
13 years 12 months ago
Performance of Hybrid Message-Passing and Shared-Memory Parallelism for Discrete Element Modeling
The current trend in HPC hardware is towards clusters of shared-memory (SMP) compute nodes. For applications developers the major question is how best to program these SMP cluster...
D. S. Henty
OSDI
2006
ACM
14 years 7 months ago
HQ Replication: A Hybrid Quorum Protocol for Byzantine Fault Tolerance
There are currently two approaches to providing Byzantine-fault-tolerant state machine replication: a replica-based approach, e.g., BFT, that uses communication between replicas t...
James A. Cowling, Daniel S. Myers, Barbara Liskov,...