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BMCBI
2010
227views more  BMCBI 2010»
13 years 10 months ago
Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
Majid Masso, Iosif I. Vaisman
BMCBI
2010
135views more  BMCBI 2010»
13 years 10 months ago
A classification approach for genotyping viral sequences based on multidimensional scaling and linear discriminant analysis
Background: Accurate classification into genotypes is critical in understanding evolution of divergent viruses. Here we report a new approach, MuLDAS, which classifies a query seq...
Ji Woong Kim, Yongju Ahn, Kichan Lee, Sung-Hee Par...
BMCBI
2007
166views more  BMCBI 2007»
13 years 10 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
BMCBI
2007
171views more  BMCBI 2007»
13 years 10 months ago
An open source infrastructure for managing knowledge and finding potential collaborators in a domain-specific subset of PubMed,
Background: Identifying relevant research in an ever-growing body of published literature is becoming increasingly difficult. Establishing domain-specific knowledge bases may be a...
Wei Yu, Ajay Yesupriya, Anja Wulf, Junfeng Qu, Mui...
BMCBI
2008
100views more  BMCBI 2008»
13 years 10 months ago
PatternLab for proteomics: a tool for differential shotgun proteomics
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
Paulo C. Carvalho, Juliana S. G. Fischer, Emily I....