Driven by new regulations and animal welfare, the need to develop in silico models has increased recently as alternative approaches to safety assessment of chemicals without animal...
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
Learning the structure of a gene regulatory network from time-series gene expression data is a significant challenge. Most approaches proposed in the literature to date attempt to ...
Background: While high-dimensional molecular data such as microarray gene expression data have been used for disease outcome prediction or diagnosis purposes for about ten years i...
Identifying functionally important sites from biological sequences, formulated as a biological sequence labeling problem, has broad applications ranging from rational drug design ...