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» Logic-Based Modeling in Systems Biology
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BMCBI
2007
147views more  BMCBI 2007»
15 years 4 months ago
Modeling biochemical transformation processes and information processing with Narrator
Background: Software tools that model and simulate the dynamics of biological processes and systems are becoming increasingly important. Some of these tools offer sophisticated gr...
Johannes J. Mandel, Hendrik Fuß, Niall M. Pa...
EMO
2005
Springer
108views Optimization» more  EMO 2005»
15 years 9 months ago
Multi-objective Model Optimization for Inferring Gene Regulatory Networks
With the invention of microarray technology, researchers are able to measure the expression levels of ten thousands of genes in parallel at various time points of a biological proc...
Christian Spieth, Felix Streichert, Nora Speer, An...
ALIFE
2008
15 years 3 months ago
Natural or Internal Selection? The Case of Canalization in Complex Evolutionary Systems
Using biological examples and theoretical arguments, the case is presented for extending the notion of natural selection to include internal selection in order to account for the e...
Alexander Riegler
RECOMB
2008
Springer
16 years 4 months ago
High-Resolution Modeling of Cellular Signaling Networks
A central challenge in systems biology is the reconstruction of biological networks from high-throughput data sets. A particularly difficult case of this is the inference of dynami...
Michael Baym, Chris Bakal, Norbert Perrimon, Bonni...
RECOMB
2002
Springer
16 years 4 months ago
A dimensionality reduction approach to modeling protein flexibility
Proteins are involved either directly or indirectly in all biological processes in living organisms. It is now widely accepted that conformational changes of proteins can critical...
Miguel L. Teodoro, George N. Phillips, Lydia E. Ka...