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» Logical systems for structured specifications
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BMCBI
2007
136views more  BMCBI 2007»
13 years 8 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
JMLR
2006
169views more  JMLR 2006»
13 years 8 months ago
Bayesian Network Learning with Parameter Constraints
The task of learning models for many real-world problems requires incorporating domain knowledge into learning algorithms, to enable accurate learning from a realistic volume of t...
Radu Stefan Niculescu, Tom M. Mitchell, R. Bharat ...
BMCBI
2004
177views more  BMCBI 2004»
13 years 8 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
NAR
2011
203views Computer Vision» more  NAR 2011»
12 years 11 months ago
Laminin database: a tool to retrieve high-throughput and curated data for studies on laminins
The Laminin(LM)-database, hosted at http://www .lm.lncc.br, is the first database focusing a noncollagenous extracellular matrix protein family, the LMs. Part of the knowledge ava...
Daiane C. F. Golbert, Leandra Linhares-Lacerda, Lu...
SIGMOD
2004
ACM
184views Database» more  SIGMOD 2004»
14 years 8 months ago
CORDS: Automatic Discovery of Correlations and Soft Functional Dependencies
The rich dependency structure found in the columns of real-world relational databases can be exploited to great advantage, but can also cause query optimizers--which usually assum...
Ihab F. Ilyas, Volker Markl, Peter J. Haas, Paul B...