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RECOMB
2007
Springer
16 years 6 months ago
Pairwise Global Alignment of Protein Interaction Networks by Matching Neighborhood Topology
We describe an algorithm, IsoRank, for global alignment of two protein-protein interaction (PPI) networks. IsoRank aims to maximize the overall match between the two networks; in c...
Rohit Singh, Jinbo Xu, Bonnie Berger
RECOMB
2004
Springer
16 years 6 months ago
The evolutionary capacity of protein structures
In nature, one finds large collections of different protein sequences exhibiting roughly the same three-dimensional structure, and this observation underpins the study of structur...
Leonid Meyerguz, David Kempe, Jon M. Kleinberg, Ro...
RECOMB
2002
Springer
16 years 6 months ago
Inferring Piecewise Ancestral History from Haploid Sequences
There has been considerable recent interest in the use of haplotype structure to aid in the design and analysis of case-control association studies searching for genetic predictors...
Russell Schwartz, Andrew G. Clark, Sorin Istrail
STOC
2006
ACM
138views Algorithms» more  STOC 2006»
16 years 6 months ago
The PCP theorem by gap amplification
The PCP theorem [3, 2] says that every language in NP has a witness format that can be checked probabilistically by reading only a constant number of bits from the proof. The cele...
Irit Dinur
STOC
2004
ACM
145views Algorithms» more  STOC 2004»
16 years 6 months ago
Using mixture models for collaborative filtering
A collaborative filtering system at an e-commerce site or similar service uses data about aggregate user behavior to make recommendations tailored to specific user interests. We d...
Jon M. Kleinberg, Mark Sandler
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