Background: Comparison of large protein datasets has become a standard task in bioinformatics. Typically researchers wish to know whether one group of proteins is significantly en...
Background: To date more than 2,1 million gene products from more than 100000 different species have been described specifying their function, the processes they are involved in a...
Background: The availability of sequences from whole genomes to reconstruct the tree of life has the potential to enable the development of phylogenomic hypotheses in ways that ha...
Indra Neil Sarkar, Mary G. Egan, Gloria M. Coruzzi...
Background: The availability of complete genomic sequences for hundreds of organisms promises to make obtaining genome-wide estimates of substitution rates, selective constraints ...
Amy Egan, Anup Mahurkar, Jonathan Crabtree, Jonath...
Driven by novel biological wet lab techniques such as pyrosequencing there has been an unprecedented molecular data explosion over the last 2-3 years. The growth of biological seq...