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» Metabolic networks analysis using convex optimization
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BMCBI
2004
150views more  BMCBI 2004»
13 years 7 months ago
Graph-based iterative Group Analysis enhances microarray interpretation
Background: One of the most time-consuming tasks after performing a gene expression experiment is the biological interpretation of the results by identifying physiologically impor...
Rainer Breitling, Anna Amtmann, Pawel Herzyk
BMCBI
2010
123views more  BMCBI 2010»
13 years 7 months ago
Computationally efficient flux variability analysis
Background: Flux variability analysis is often used to determine robustness of metabolic models in various simulation conditions. However, its use has been somehow limited by the ...
Steinn Gudmundsson, Ines Thiele
ISQED
2002
IEEE
111views Hardware» more  ISQED 2002»
14 years 18 days ago
Optimization of the Power/Ground Network Wire-Sizing and Spacing Based on Sequential Network Simplex Algorithm
This paper presents a fast algorithm to optimize both the widths and lengths of power/ground networks under reliability and power dip/ground bounce constraints. The spacesizing wh...
Ting-Yuan Wang, Charlie Chung-Ping Chen
GECCO
2004
Springer
150views Optimization» more  GECCO 2004»
14 years 1 months ago
Systems Biology Modeling in Human Genetics Using Petri Nets and Grammatical Evolution
Understanding the hierarchical relationships among biochemical, metabolic, and physiological systems in the mapping between genotype and phenotype is expected to improve the diagno...
Jason H. Moore, Lance W. Hahn
VLDB
1998
ACM
97views Database» more  VLDB 1998»
13 years 12 months ago
Design and Analysis of Parametric Query Optimization Algorithms
Query optimizers normally compile queries into one optimal plan by assuming complete knowledge of all cost parameters such asselectivity and resourceavailability. The execution of...
Sumit Ganguly