Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...
Background: Evolutionary analysis provides a formal framework for comparative analysis of genomic and other data. In evolutionary analysis, observed data are treated as the termin...
Thomas Hladish, Vivek Gopalan, Chengzhi Liang, Wei...
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...
Requirement analysis continues to be one of the most critical and challenging phases during the software development process. Many object-oriented methodologies identify three pri...
Peter J. Clarke, Yingbo Wang, Tuan L. Cameron, Yal...
The combination of fully sequence genomes and new technologies for high density arrays and ultra-rapid sequencing enables the mapping of generegulatory and epigenetics marks on a g...