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» Methods for Predicting Target Sites of Transcription Factors
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NAR
2011
204views Computer Vision» more  NAR 2011»
12 years 11 months ago
CLIPZ: a database and analysis environment for experimentally determined binding sites of RNA-binding proteins
The stability, localization and translation rate of mRNAs are regulated by a multitude of RNAbinding proteins (RBPs) that find their targets directly or with the help of guide RNA...
Mohsen Khorshid, Christoph Rodak, Mihaela Zavolan
BMCBI
2006
110views more  BMCBI 2006»
13 years 8 months ago
Modelling the network of cell cycle transcription factors in the yeast Saccharomyces cerevisiae
Background: Reverse-engineering regulatory networks is one of the central challenges for computational biology. Many techniques have been developed to accomplish this by utilizing...
Shawn Cokus, Sherri Rose, David Haynor, Niels Gr&o...
BMCBI
2007
149views more  BMCBI 2007»
13 years 8 months ago
Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors
Background: Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivate...
Xueping Yu, Jimmy J. Lin, Donald J. Zack, Jiang Qi...
BMCBI
2008
126views more  BMCBI 2008»
13 years 8 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
BMCBI
2007
152views more  BMCBI 2007»
13 years 8 months ago
Bioinformatic identification of novel putative photoreceptor specific cis-elements
Background: Cell specific gene expression is largely regulated by different combinations of transcription factors that bind cis-elements in the upstream promoter sequence. However...
Charles G. Danko, Vera A. McIlvain, Maochun Qin, B...